**7. Conclusion**

A whole body scan obtained with the administration of a diagnostic or therapeutic dose of radioiodine has a definite role in the management of patients with well differentiated thyroid cancer after total thyroidectomy. Accurate interpretation of the scan requires a thorough knowledge and understanding of potential confounding factors for uptakes on the scan, and recognition of the variable causes of false positive uptake will provide correct prognostic inferences and prevent inappropriate therapeutic interventions. In addition, the cause of radioiodine uptake on the scan is always evaluated in conjunction with the serum thyroglobulin level and the clinico-radiological results in order to lessen the chance of an incorrect conclusion about the uptakes.

This chapter was written to make readers consider a broad variety of diseases as the causes of the uptake on the radioiodine whole body scan and I have demonstrated a wide variety of causes of false positive uptakes on these scans.
