**2.4.2.3 [18F]T794, [18F]T807 and [18F]T808**

Recently, Kolb and colleagues reported development of PET radiopharmaceuticals with high binding affinity and selectivity for tau tangles (Szardenings, et al., 2011), and three lead compounds were identified: [18F]T794, [18F]T807 and [18F]T808. Initial autoradiographical and rodent microPET studies suggest these compounds have the desired binding affinity for tau and good selectivity for tau over amyloid, to fill the void in clinical tau PET imaging. Translation into the clinic is underway, although human imaging studies with these compounds have also yet to be reported.
