**8.1.8.3 Cyclotron Cycle**


11. Monitor your working area before and after each assignation and whenever a

13. Monitor your hands before living controlled area and return to 12 until background

14. Record every activity (cyclotron, Hot Lab, Synthsys lab, Fractionation Lab) in

17. In case of inhalation or ingestion follew corresponding emergency procedure as it is

In such a large facility it is mandatory to exist an ad hoc committee known s "Radiation Safety Committee" (RSC) as it is establish in Venezuelan safety standard NVC3299. In our

For radiation area classification, national standard recommendation will be follow as in NVC 2257: Any area must be classified as "Controlled" if in any moment of daily operation the exposition rate is above 0.5 mR/h. In this sense , cyclotron room, synthesis lab, hot lab, injection room pet/ct room are controlled areas by default. Classification of different areas will be consult to RSC and RSO and will be solve only after 24 h continuous measurements, and any other consideration in standard classification may be voted and solved by more that

This is the figure that will take all the decisions regarding al RS concerns and its decisions

In radioisotope uses (for diagnostic or therapies) any patient application can be supervised by committee and logs must be all time up to date. All the details for all the task mentioned above must be clearly describe in each procedure manual and clearly understand by any of

Notification chain must also be clearly establish and accomplish from personnel who needs

• In Hot Lab 18F ions are measured in activity, pureness, pyrogenicity, volume, etc • Synthesis Lab FDG is produced by substitution of oxygen ion by the activated fluorine

contamination is suspected

corresponding log

1. Radiation Safety Officer

written

**8.1.8.1** 

**8.1.8.2** 

75% of delegates

the participant of each task

**8.1.8.3 Cyclotron Cycle** 

12. Wash your hands before living controlled area

15. Any unusual event must be report in corresponding log 16. In any radiological event communication chain must be follow

2. One delegate from maintenance and engineering department

Many other specialist, physician, physicist, chemist can be include

must be voted to win with more of the 75% of the committee delegates.

• In cyclotron room protons hits water target transmuting 16O into 18F.

to report, thru RSO, until the National Regulatory Authority

ion inside the molecular chain yielding to labeled 18FDG

3. One delegate from directive or administrative board

is reached. In any case contact RSO

case, this comitte must ever be conformed by:

4. One delegated of security department 5. One delegate from technician staff 6. One delegate from nursing staff 7. One delegated from physician (at least)
