**10. Management of urinary tract infections in diabetics**

Generally, treatment of UTI is similar in both diabetic patients and nondiabetic patients [5]; however, the choice of antibiotics in UTI patients with diabetes is one of the important considerations in the therapeutic management. Possible drug interactions between antimicrobials and antidiabetics or certain antibiotics may lead to impaired glucose homeostasis.

UTI treatment in diabetes patients depends on various factors including [5];


Moreover, UTI treatment varies based on patient's age, sex, infecting agent, underlying disease, and whether there is lower or upper urinary tract involvement. Several clinical trials revealed that increasing trends of resistance to many antimicrobials with the increasing trend of antibiotic resistance in *E. coli*, with limited therapeutic options, the management of urinary tract infections is likely to become complicated.
