**4. Conclusion**

Novel electrochemical techniques for the detection of biomarkers of breast cancer have been established using the remarkable progress in nanotechnology and biosensor techniques. Effective electrochemical detection systems are combined with immunology guidelines to host different antibody-complex reactions on the transducer surface and quantitatively identify the biomarkers. Current electrochemical biosensors, such as DNA or immunosensors, have extraordinary sensitivity that is important for early detection of cancer. The integration of electrochemical instruments with nano-scale materials provides a unique multiplexing mechanism for various cancer marker simultaneous measurements. However, before marketing the developed biosensors for actual clinical practices for the detection of biomarkers for breast cancer, important gaps and approaches need to be addressed and implemented.
