**Acknowledgements**

The second opportunity to work with IntechOpen publishers has been excellent. I must thank my colleague Dr. Nithin in crafting the manuscript and it was his enthusiasm which led to a detail manuscript. We both would like to thank our respective parents for all the support and blessings. My wife (Reshmi) and Nithin's wife (Dr. Nikhila) respectively have been the greatest source of support. We also would like to thank our organization (HCG Apex Cancer Centre in Mumbai, India) for encouraging academic engagements in all possible aspects.
