**10. Rotterdam Convention**

There are relatively few studies that have examined the persistence of endosulfan in soil under field conditions. Degradation rates strongly depend on the soil conditions (particularly

The Environmental Protection Agency (EPA) indicates that concentrations above 0.22 μg L−<sup>1</sup>

avoid intoxication from water consumption, fish or shellfish from water bodies near fields where the pesticide is used, concentration limits need to be established. For air concentrations, the limit recommended by the National Institute for Occupational Safety and Health

Health authorities and legislators have implemented strategies for the use of pesticides due to the thousands of deaths reported every year due to the indiscriminate use of these substances. In 1985, the code of conduct on the distribution and use of pesticides by the United Nations Food and Agriculture Organization (FAO) was published to regulate the use and availability of pesticides. For a safe use of pesticides, several actions need to be undertaken; in the case of farmers, education on the application of products needs to be provided, government inspectors require to check the application of pesticides in the crop fields within the framework of

This convention that deals with persistent organic pollutants (POPs) is an international treaty for the protection of human health and the environment from the effects of chemical compounds that remain for long periods in the environment, are widely distributed, and accumulate in the fatty tissues of humans and animals. The exposure to these compounds can result in serious health problems, such as some cancers, birth defects, and deficient immune and

The POP Review Committee (POPRC) is a scientific body created to review the chemical compounds that are proposed for inclusion in the text of the Annexes A, B, or C of the convention. Endosulfan was presented for inclusion in Annex A by the European Union in November 2007. The Committee of Review issued the decision POPRC-4/5, it specifies that "the selection criteria for endosulfan have been met" and a working group was established to elaborate a

The information was requested from Parties for Annex F as well as the review of additional information on the adverse effects of endosulfan on human health [12, 15]. After evaluating the risk profile and finalizing the risk management evaluation, the POPRC, at its sixth meeting held in Geneva from October, 11 to 15, 2010, decided to recommend to

draft risk profile in accordance with Annex E of the Convention [12].

(chronic) have adverse impacts on the health of aquatic organisms. To

soil water content and ambient temperature).

[22, 24].

FAO's Integrated Pest Management System [25].

(acute) and 0.05 μg L−<sup>1</sup>

10 Persistent Organic Pollutants

(NIOSH) is 0.1 mg m−<sup>3</sup>

**8. Regulation of endosulfan**

**9. Stockholm convention**

reproductive systems, among others [12].

This exchange under the Rotterdam Convention on "prior informed consent" applies to banned or restricted chemicals and to the severely hazardous pesticide preparations listed in Annex III. Currently, there are more than 30 chemical products to which the PIC procedure applies. At the fifth meeting of the Conference of the Parties to the Rotterdam Convention that took place in Geneva, Switzerland, between June 21 and 24, 2011, it was agreed to include the endosulfan pesticide in Annex III of the Convention.

Previously, the seventh meeting of the Chemical Review Committee, held in Rome from March 28 to April 1, 2011, recommended the inclusion of a number of new chemicals in this Annex, including the pesticide endosulfan that had recently added to the list of the Stockholm Convention of chemical substances that must be eliminated [26].
