Preface

Chapter 8 **Placenta Therapy: Its Biological Role of Anti-Inflammation and**

Kyeong Mee Park, Dong Pill Cho and Tae Hwan Cho

**Regeneration 113**

**VI** Contents

Because normal placentation is vital for maintaining gestation and optimal fetal development, supplying nutrients, exchanging gases, and eliminating metabolic waste products, any disor‐ ders in placental functions can cause several pregnancy complications. *The Placenta* focuses on the natural, developmental, biochemical, immunological, and molecular basis of developing the placenta (placental hemodynamics: invasion, proliferation, and migration). The book re‐ views the factors that contribute to the fetoplacental axis, the placenta-derived mesenchymal stromal cells, and modulation of immunity and inflammation. *The Placenta* also explores the complications of abnormal placentation (accreta and beyond) and their management. Finally, placental therapy and the biological roles of antiinflammation and regeneration are proved. Scientists, physicians, embryologists, and lay readers engaged in placental studies or practice will find that this book offers insight into all areas of placenta research.

> **Ahmed R.G.** Associate Professor Dr. of Developmental and Experimental Biology Division of Anatomy and Embryology Zoology Department Faculty of Science Beni-Suef University, Egypt

**Chapter 1**

**Provisional chapter**

**Chorioangioma of Placenta**

**Chorioangioma of Placenta**

http://dx.doi.org/10.5772/intechopen.79993

Additional information is available at the end of the chapter

Additional information is available at the end of the chapter

hemolytic anemia, polyhydramnios, IUGR, and IUFD.

**Keywords:** chorioangioma, fetus, placenta, polyhydramnios, villi

DOI: 10.5772/intechopen.79993

The human placenta is a villous hemochorial structure. It is attached to the uterine wall and establishes connection between the mother and the fetus through the umbilical cord and thus plays a critical role in maternal fetal transfer. It is developed from two sources: fetal chorion frondosum and maternal decidua basalis. Various abnormal conditions have been reported with the placenta and the placental chorioangioma is one of them. Chorioangioma of placenta is the commonest benign tumor of the placenta. It consists of a benign angioma arising from the chorionic tissue. It has been found to be associated with many serious complications such as nonimmune hydrops, congenital abnormalities,

The human placenta is discoid in shape and is a villous hemochorial structure [1, 2]. The placenta is attached to the uterine wall and establishes connection between the mother and the fetus through the umbilical cord and thus plays a critical role in maternal fetal transfer [2]. It has a complex synthetic capacity and plays a role in the immunologic acceptance of fetal

The placenta is developed from two sources. The principal component is fetal which develops from the chorion frondosum, and the maternal component consists of decidua basalis (**Figure 1**) [2].

> © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use,

distribution, and reproduction in any medium, provided the original work is properly cited.

Rubby Das

Rubby Das

**Abstract**

**1. Introduction**

allograft [2].

**2. Development**

#### **Chapter 1 Provisional chapter**

#### **Chorioangioma of Placenta Chorioangioma of Placenta**

#### Rubby Das Rubby Das

Additional information is available at the end of the chapter Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/intechopen.79993

**Abstract**

The human placenta is a villous hemochorial structure. It is attached to the uterine wall and establishes connection between the mother and the fetus through the umbilical cord and thus plays a critical role in maternal fetal transfer. It is developed from two sources: fetal chorion frondosum and maternal decidua basalis. Various abnormal conditions have been reported with the placenta and the placental chorioangioma is one of them. Chorioangioma of placenta is the commonest benign tumor of the placenta. It consists of a benign angioma arising from the chorionic tissue. It has been found to be associated with many serious complications such as nonimmune hydrops, congenital abnormalities, hemolytic anemia, polyhydramnios, IUGR, and IUFD.

DOI: 10.5772/intechopen.79993

**Keywords:** chorioangioma, fetus, placenta, polyhydramnios, villi
