**2. Types**

#### **2.1 Head and neck sarcoidosis**

This may occur in combination with, or independent of, CNS sarcoidosis; this has been found in 10–15% of patients with systemic disease [7].

#### **2.2 Orofacial sarcoidosis**

Although orofacial presentations of sarcoidosis are uncommon, it is important because of the fact that sarcoidosis in the orofacial region may indicate the development of systemic involvement [4]. Generally, in the case of orofacial sarcoidosis, swelling of the salivary glands is observed. Xerostomia may or may not be present; and bilateral enlargement of the parotid glands may be affected in 4–6% of the cases [8].

#### **2.3 Orofacial granulomatosis**

Orofacial granulomatosis (OFG), defined by Wiesenfeld in 1985, encompasses conditions characterized by non-necrotizing granulomatous inflammation of soft tissues in the oral and maxillofacial region that present clinically with labial enlargement, perioral and/or mucosal swelling, oral ulcerations, gingivitis, and a variety of other orofacial features [9]. The clinical manifestations can be highly variable, and this variability makes it difficult to diagnose. OFG is a disease that encompasses a broad range of presentations, which may include oral manifestations of a systemic condition such as Crohn's disease (CD), sarcoidosis, granulomatosis with polyangiitis, and Melkersson-Rosenthal syndrome [10]. On the other hand, some studies say that OFG displays a spectrum of diseases ranging from granulomatous cheilitis to patients with granulomas involving other orofacial tissues, with or without facial nerve palsy and plicated tongue (Melkersson-Rosenthal syndrome) [11]. According to recent evidence, OFG can also be classified into three categories [12, 13], namely:

