1. Introduction

Platelet concentrates (PCs) for surgical use are innovative tools of regenerative medicine and dentistry and were widely studied in oral and maxillofacial surgery. PCs are blood extracts, applied to surgical sites, injuries, or wounds, a safe and effective way to promote soft tissue healing and bone growth. The most frequently used substrate, platelet-rich fibrin (PRF) is a member of platelet concentrates developed by Choukroun and colleagues [1]. PRF is an autologous matrix, in which cytokines and cells are released after a short period [2].

The aim of this chapter is to describe the potential functions of PRF for bone grafting in oral and maxillofacial surgery.

There are different types of PRF in local use.
