7. Prepared platelet-rich lysate (PRF-L)

A newer application of PRF is the prepared platelet-rich lysate (PRF-L). In this technique, after PRF preparation, it is incubated at 37C in a humidified atmosphere of 5% CO2 and 95% air. The exudate, which is collected, is referred to as PRF lysate. It is said to be a good source of several growth factors. In a study, it is found that PRF-L can significantly improve the proliferation index, collagen deposition and migration rates in chronically UVA-irradiated human dermal fibroblasts [13]. This is a new technique that requires further studies.
