**15. OPAP appliances (oral appliance + CPAP device)**

nCPAP device applies very high pressure and high airflow rate which leads to irritation of nasal, oral, and throat mucosa and decreases patient compliance. When MAD-type oral appliances are combined with CPAP device, the pressure given by nCPAP diminishes; irritation of nasal, oral, and throat mucosa decreases; and patient compliance and treatment success increase. The adaptation of CPAP and MAD appliance should be done by a dental sleep specialist [10, 18].
