Meet the editors

Dr. Ozgur Karcioglu, MD, graduated from residency in Dokuz Eylul University Medical School, Department of Emergency Medicine, Turkey, in 1998. He completed the "International Emergency Medicine" Fellowship in Penn State University in 2005. He now serves as the Chair of the Department of Emergency Medicine, Istanbul Education and Research Hospital. Dr. Karcioglu worked as a founder and board member of the

Emergency Medical Association of Turkey after 1995. He has published more than 130 articles in scientific journals, contributed in 4 books as editor, and authored 35 chapters. Recently, he edited the book Trauma Surgery with the collaboration of IntechOpen. He is also an instructor of the Advanced Cardiac Life Support Course.

Dr. Banu Arslan, MD, MS, completed her emergency medicine residency at the University of Health Sciences, Istanbul Education and Research Hospital, in 2015. She worked at Kiziltepe Government Hospital, Mardin, from 2015 to 2016 where she gained experience in combat injuries and trauma care. She attended an Academic English Program at Southern Methodist University, TX, USA, between 2016 and 2017. Dr. Arslan worked

as an attending emergency medicine physician, involved in teaching and clinical activities at Marmara University, Pendik Education and Research Hospital, from 2017 to 2018. Currently, she is studying MS in Healthcare Management at the University of Texas at Dallas. She has current certifications in ATLS, ACLS, and PALS. Her research interests are trauma care, toxicology, and healthcare financial management.

Contents

**Section 1**

*and Violeta Ștreangă*

Forensic Toxicology *by Sahar Y. Issa*

*and Marian N. Unachukwu*

Nephrotoxic Effects of Drugs

**Section 2**

Cosmetics

*by Azade Sari*

General Approach to Poisoned Patient *by Ehab Said Aki and Jalal Alessai*

Poisoning in the Pediatric Intensive Care Unit

**Preface III**

General Principles in the Management of Intoxications **1**

**Chapter 1 3**

**Chapter 2 23**

**Chapter 3 45**

Organ-Specific Effects and Toxicological Agents **57**

**Chapter 4 59**

**Chapter 5 77**

**Chapter 6 101**

Review of Health Hazards and Toxicological Effects of Constituents of

Mechanism and Health Effects of Heavy Metal Toxicity in Humans *by Godwill Azeh Engwa, Paschaline Udoka Ferdinand, Friday Nweke Nwalo* 

*by John Kanayochukwu Nduka, Henrietta Ijeoma Kelle and Isaac Omoche Odiba*

*by Nicolai Nistor, Otilia Frăsinariu, Aniela Rugină, Irina Mihaela Ciomaga* 

## Contents


Preface

The term "poison" was first used in ancient French literature dating back to the Thirteenth century. Poisoning is a process in which an organism becomes severely chemically harmed by a toxic substance or venom. Poisoning, or the hazardous effects of foreign substances on the metabolism, has long been recognized as one of the greatest threats to public health. Industrialization, urbanization, economics, changes in communication, and availability of toxic agents, including various medicines, are among many factors that have an impact on patterns of human poisoning

It is important to increase awareness of the risk factors for poisoning with different substances: e.g., illicit drugs, industrial exposure, warfare agents, foods, and prescribed medicines, all of which can threaten an organism's homeostasis permanently or temporarily. On the other hand, standard medical education encompasses only a small part of toxicology and gives just a hint of how to manage a poisoned patient. Another point of view suggests that the importance of poisoning mandates a variety of clinicians, including almost all disciplines in medicine, namely, family physicians, emergency medicine physicians, pediatricians, and internists, who all

Therefore, this book is intended for clinicians in routine practice who are willing to reach the contemporary literature data on different scenarios of poisoning and new

**Ozgur Karcıoglu, MD, FEMAT**

Department of Emergency Medicine, University of Health Sciences,

Naveen Jindal School of Management,

Healthcare Management and Leadership Program,

Istanbul Education and Research Hospital,

Professor,

USA

Fatih, Istanbul

**Banu Arslan, MD, MS**

University of Texas at Dallas,

have advanced knowledge of the management of poisoned patients.

techniques developed for elimination, decontamination, and treatment.

in the modern era.
