**Meet the editor**

Dr. Chai received his Ph.D. from the City University of New York in 1998 and completed his postdoctoral training at Harvard University in 2001. He then served in the Department of Veterans Affairs of the United States as a principal investigator (2002–2016) in affiliation with the School of Medicine, University of California in Irvine. Currently, he is a professor at Baotou Medical College,

Inner Mongolia University of Science and Technology. He has published dozens of research articles on various subjects, including zoology, cardiovascular biology, gastroenterology, and cancer biology. He has been a member of AGA, AHA, ASBMB, and several other professional organizations, and has also served on the editorial board of multiple journals.

Contents

**Preface VII**

Jianyuan Chai

Ciprandi

Chapter 1 **Introductory Chapter: Esophagus and Esophageal Cancer 1**

Chapter 4 **The Clinical Relevance of Gastroesophageal Reflux Disease and Laryngopharyngeal Reflux in Clinical Practice 47**

Aragona Salvatore Emanuele, Mereghetti Giada and Giorgio

Chapter 2 **Immunotherapy for Esophageal Cancer 11**

Chapter 3 **Prevention and Management of Complications from**

Chapter 5 **The Role of Esophagus in Voice Rehabilitation of**

Ljiljana Širić, Marinela Rosso and Aleksandar Včev

Tian Wang and Yi Zhang

**Esophagectomy 29** Jacqueline Oxenberg

**Laryngectomees 67**
