Preface

*Contemporary Pediatric Hematology and Oncology* is the first edition, and has been a wonderful opportunity to bring together the expertise of hematology and oncology doctors from different communities. The book is designed to be the first step in advanced practice working with pediatric hematology/oncology patients. Specific issues related to young children and adolescents with cancer and hematologic disorders are discussed.

Three contributors and two editors participated in writing this book. The book is divided into four sections: Introduction to Pediatric Hematology and Oncology, Nocturnal Enuresis in Sickle Cell Anemia, Inherited Bone Marrow Failure Syndromes, and Malignant Tumors in Children. Many tables and illustrations are included for quick reference in the clinical setting.

Section I focuses on a general introduction to pediatric hematology and oncology and the great evolution that had been made regarding recent and advanced molecular diagnostic methods that have paved the way for novel therapeutic potentials in the field of pediatric hematology and oncology.

Section II focuses on benign hematology, including hemoglopanopathies and unusual clinical associations, with emphasis on how to diagnose and treat these disorders.

Section III illustrates the dilemma of bone marrow failure with a comprehensive overview of the genetic bases of different types, etiology, symptoms and clinical signs, diagnostic and laboratory testing, new areas of classification, therapeutic modalities, and prognosis.

Section IV focuses on pediatric cancers—the leukemias, lymphomas, and solid tumors. The most common pediatric tumors as well as some rare tumors are discussed in regard to epidemiology, etiology, molecular genetics, symptoms and clinical signs, diagnostic and laboratory testing, staging and classification, treatment, prognosis, and follow-up care.

The editors of *Contemporary Pediatric Hematology and Oncology* wish to recognize, thank, and acknowledge everyone who participated in writing this book. We are profoundly aware of the personal time and commitment that was devoted to make this an outstanding resource, and we are grateful. It is our hope that all healthcare, academic, and clinical practitioners in advanced clinical practice will find this publication useful, and that it will enrich knowledge and improve care for children and adolescents with cancer and hematologic disorders.

> **Marwa Zakaria** Zagazig University, Egypt

> **Tamer Hassan** Zagazig University, Egypt

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Section 1

Introduction to Pediatric

Hematology and Oncology

Section 1
