**Author details**

Mauro Bozzola1,2\*, Federico Manai3 , Chiara Montalbano4 , Alberto Azzalin3 , Elena Bozzola5 , Alberto Villani<sup>5</sup> and Sergio Comincini3

\*Address all correspondence to: mauro.bozzola@unipv.it

1 Department of Internal Medicine and Therapeutics, Unit of Pediatrics and Adolescentology, University of Pavia, Pavia, Italy

2 Onlus "Il Bambino e il suo pediatra", Galliate (Novara), Italy

3 Department of Biology and Biotechnology, University of Pavia, Pavia, Italy

4 Foundation IRCCS San Matteo, Pavia, Italy

5 Department of Pediatrics, Pediatric and Infectious Diseases Unit, Bambino Gesù Children Hospital IRCCS, Rome, Italy

© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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*The Emerging Role of the Autophagy Process in Children with Celiac Disease: Current Status…*

S, et al. Cargo recognition failure is responsible for inefficient au ophagy in Huntington's disease. Nature Neuroscience. 2010;**13**(5):567-576

[9] Codogno P, Mehrpour M, Proikas-Cezanne T. Canonical and non-canonical autophagy: Variations on a common theme of self-eating? Nature Reviews. Molecular Cell Biology. 2011;**131**:7-12

[10] Naser SA, Arce M, Khaja A, Fernandez M, Naser N, Elwasila S, et al. Role of ATG16L, NOD2 and IL23R in Crohn's disease pathogenesis. World Journal of Gastroenterology.

[11] Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-

2008;**456**(7219):264-268

induced IL-1beta production. Nature.

[12] Henckaerts L, Cleynen I, Brinar M, John JM, Van Steen K, Rutgeerts P, et al. Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

Inflammatory Bowel Diseases.

[13] Gros F, Arnold J, Page N, Décossas M, Korganow AS, Martin T, et al. Macroautophagy is deregulated in murine and human lupus T lymphocytes. Autophagy.

[14] Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb AL, Frausto RF, et al. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy. 2009;**5**(2):152-158

[15] Ireland JM, Unanue ER. Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. The Journal of Experimental Medicine.

2011;**17**(6):1392-1397

2012;**8**(7):1113-1123

2011;**208**(13):2625-2632

2012;**18**(5):412-424

*DOI: http://dx.doi.org/10.5772/intechopen.80692*

[1] Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA. American College of Gastroenterology ACG clinical guidelines: Diagnosis and management of celiac disease. The American Journal of Gastroenterology. 2013;**108**(5):656-676

[2] Bonamico M, Thanasi E, Mariani P, Nenna R, Luparia RP, Barbera C, et al. Società Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica. Duodenal bulb biopsies in celiac disease: A multicenter study. Journal of Pediatric

Gastroenterology and Nutrition.

[3] Oberhuber G, Granditsch G, Vogelasng H. The histopathology of celiac disease: Time for a standardized report scheme for pathologists. European Journal of Gastroenterology & Hepatology. 1999;**11**:1185-1194

[4] Lee AR, Ng DL, Zivin J, Green PH. Economic burden of a gluten-free diet. Journal of Human Nutrition and

Dietetics. 2007;**20**:423-430

[5] Barratt SM, Leeds JS, Sanders DS. Quality of life in celiac disease is determined by perceived degree of difficulty adhering to a gluten-free diet, not the level of dietary adherence

ultimately achieved. Journal of Gastrointestinal and Liver Diseases.

[6] Deretic V, Saitoh T, Akira S.

Biology. 2010;**190**(6):1023-1037

[8] Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik

Autophagy in infection, inflammation and immunity. Nature Reviews. Immunology. 2013;**13**(10):722-737

[7] Winslow AR, Chen CW, Corrochano S, Acevedo-Arozena A, Gordon DE, Peden AA, et al. α-Synuclein impairs macroautophagy: Implications for Parkinson's disease. The Journal of Cell

2011;**20**:241-245

2008;**47**(5):618-622

**References**

*The Emerging Role of the Autophagy Process in Children with Celiac Disease: Current Status… DOI: http://dx.doi.org/10.5772/intechopen.80692*
