**5. Conclusion**

In conclusion, this chapter has reviewed the current commercially and laboratory-based developed POCT devices and the challenges to be faced with for a rapid and simple test of celiac disease. It is expected that more efforts of multidisciplinary research involved in immunology, lateral flow technology, microfluidics, nanotechnology, and genetics could provide a great opportunity for the fast, accurate, and early diagnosis of celiac disease, dramatically improving the quality of human life.
