**Author details**

*Celiac Disease - From the Bench to the Clinic*

Because it is not possible to calculate the risk for the various world populations, there are many where the absence of disease prevalence data does not allow this calculation to be carried out, an estimate for populations of Caucasian origin seems to produce very close results suggesting that calculations are accurate in these populations. Considering the relevance of risk demonstrated by the most prevalent and important genotypes for the development of CD, DQ2.5/DQ2.5, DQ2.5/DQ2.2, and DQ2.5/DQ8, it can be recommend that population studies, especially those for clinical diagnosis, which until now considering the risk for development CD associated only to the presence of the DQ2.5/DQ2.5 and DQ2.5/DQ8 genotypes, which consider the inclusion of the DQ2.5/DQ2.2 genotype in their research, because this genotype does indeed pose a high risk for CD development and should not be

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neglected.

**Figure 3.**

**Figure 2.**

*Calculated Risk—Murad et al. [64].*

*Calculated Risk (Brazilian population)—Almeida et al. [2].*

Yanna Karla de Medeiros Nóbrega Applied laboratory analysis, Graduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, College of Health Sciences, University of Brasilia, Brasília, DF, Brasil

\*Address all correspondence to: yannanobrega@gmail.com

© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
