*3.3.2 Stabilizers of TTR tetramere*

Nonsteroidal anti-inflammatory drugs (NSAIDs) and tafamidis meglumine inhibit TTR tetramere degradation and therefore formation of amyloidogenic monomers. NSAIDs have structural resemblance to thyroxine, a natural tetramere stabilizer. Diflunisal and tafamidis are disease modifying treatments for fATTR.
