**2. Methods**

A total of 9152 candidate publications was identified during a comprehensive literature search using PubMed, Google Scholar™, EBSCOHost, and Bioline International. Search terms included various combinations of "resuscitative endpoints," "traumatic shock," "biomarkers in shock," "study," and "clinical trial." Within the larger subset of candidate publications, 70 studies were deemed suitable in the development of this chapter's content.
