**6.1 Hypoxia**

Acute hypoxia is frequently the first sign of AFE and has been reported to be present in >90% of patients according to the AFE National Registry [2]. Maternal oxygenation should be monitored by pulse oximetry. The degree of respiratory compromise will determine the approach for oxygen delivery. Regardless of the route of delivery, oxygen should be administered immediately and judiciously. Intubation is often necessary but may not be required in all cases.
