*5.2.1 VD pleiotropy after KT: proteinuria and renal protection*

Observational studies linked poor VD status to poorer graft outcomes [86]. Our results also demonstrated that higher VD is associated with lower post-transplant proteinuria [87]. However, interventional studies did not fully support the VD– graft function association. Cholecalciferol supplementation failed to demonstrate renoprotection in prospective study [88]. However, in a recent prospective placebocontrolled study, paricalcitol ameliorated proteinuria in KTRs [89].
