**5. Conclusion**

Pharmacokinetic, pharmacodynamic, intraspecies and extraspecies scaling are some parameters that can affect physiological functions of antimicrobials in goats. Lack of judicious and extralabel use of antimicrobials in goats could cause high tissue residues and development of resistance by susceptible microorganisms against the antimicrobials in both goats and humans. Tissue residues of sulfadimidine may cause Stevens-Johnson syndrome in the vulnerable individuals. Dehydrated goats may be more susceptible to antimicrobial toxicity. GFR can be used to assess the level of kidney damage caused by antimicrobials, and rehydration therapy is useful in dissolution of antimicrobial crystals formed in the kidney. In case of fervent need for extralabel use of antimicrobials, the relevant formulas reported herein could be used to translate goat dose to human dose and vice versa.
