5.2.2.1 Sporotrichosis

Sporotrichosis, skin infection of a dimorphic fungus Sporothrix schenckii particularly endemic in tropical and subtropical areas, is mediated by traumatic inoculation from soil or plants [48]. Skin biopsy material of sporotrichosis shows suppurative granuloma formation in the dermis. Periodic acid-Schiff-reactive small yeast-like fungal cells phagocytized by macrophages or multinucleated giant cells were reactive with the patient's own serum (Figure 26) [20, 21, 23].
