**3. Extra virgin olive oil (EVOO)**

EVOO is one of the most important components of Mediterranean diet having many health benefits. At first, excess of (MUFA) especially oleic acid, was thought

**Figure 9.**

**Figure 10.**

**75**

*Metabolism of EVOO.*

*Chemical structure of EVOO.*

*In Silico Proteomics EVOO Therapy for Lipid Lowering in the Patients of Diabetes Mellitus*

*DOI: http://dx.doi.org/10.5772/intechopen.82294*

**Figure 8.** *Representing health benefits of extra virgin olive oil.*

*In Silico Proteomics EVOO Therapy for Lipid Lowering in the Patients of Diabetes Mellitus DOI: http://dx.doi.org/10.5772/intechopen.82294*

**Figure 9.** *Chemical structure of EVOO.*

**2.8 Prevention of diabetes**

*Biochemical Testing - Clinical Correlation and Diagnosis*

**3. Extra virgin olive oil (EVOO)**

**Figure 8.**

**74**

*Representing health benefits of extra virgin olive oil.*

As diabetes is multifactorial gene disorder, as genetic information and environmental effects both play a role in this disease. Type 1 diabetes is comparatively less affected with environmental factors but type 2 does. So, it is difficult to stop the onset of type 1 diabetes, but for type 2 diabetes there are many known preventive measures. These preventive measures include maintaining normal body weight, use of healthful diet and regular physical exercise. Changing in eating habits are known to reduce the risk of diabetes, such as taking whole grain diet, using diet with good fats (nut, fish) and reducing use of saturated fats (red meat). But above all, limit use of sweet edibles is the most important and effective preventive measure as well as in controlling the complication of diabetes. In addition, if an individual quits smoking,

EVOO is one of the most important components of Mediterranean diet having many health benefits. At first, excess of (MUFA) especially oleic acid, was thought

the risk of onset of diabetes reduces many folds (**Figure 7**) [41].

**Figure 10.** *Metabolism of EVOO.*

as the major beneficial constituent of virgin olive oil. Most important health benefit of EVOO (**Figure 8**) is improved cardiovascular heal, reduction of inflammation and oxidative stress. It is used in Mediterranean diet since many decades. Studies suggested that Mediterranean food specimen along with EVOO lowers the risk of heart disorders as compared to controls. Other studies reported that EVOO improve hyperglycemia and lipid level in patients with dysfunctional fasting glucose (Roberto *et al.*, 2016). Almost 200 'minor particles' in the un-saponifiable portion of olive oil comprise about 2% of the total weight of EVOO [42–63].

hallmark of the diabetes that is why EVOO is compound of choice for the therapy of diabetes. The phenols in the EVOO are the major components responsible for these beneficial effects. Due of the fact that the EVOO therapy for the treatment of diabetes has never been studied before in the diabetic population of Pakistan we step forward and to use this natural compound as a therapy for treatment of type 2

*In Silico Proteomics EVOO Therapy for Lipid Lowering in the Patients of Diabetes Mellitus*

There is no study available in Pakistan that support the therapeutic effect of EVOO in type 2 diabetes so got the idea to prove the therapeutic value of EVOO in the Diabetic population of Pakistan, for this we selected the Lahore region that is

diabetes [72–80].

**Author details**

Lahore, Pakistan

**77**

Muhamamd Suhail and Samreen Riaz\*

provided the original work is properly cited.

Department of Microbiology and Molecular Genetics, University of the Punjab,

© 2020 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

\*Address all correspondence to: samreen.mmg@pu.edu.pk

one of the populated city of Pakistan.

*DOI: http://dx.doi.org/10.5772/intechopen.82294*
