**Author details**

Umer Farooq1 , Muhammad Wajid Ullah2 , Qiaoli Yang1 and Shenqi Wang1 \*

1 Advanced Biomaterials and Tissue Engineering Centre, Huazhong University of Science and Technology, Wuhan, P. R. China

2 Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, P. R. China

\*Address all correspondence to: shenqiwang131@hust.edu.cn

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**187**

*Applications of Phage-Based Biosensors in the Diagnosis of Infectious Diseases, Food Safety…*

water using luminescent and visual readout. Analytical and Bioanalytical Chemistry. 2014;**406**:5685-5693. DOI:

[8] Kulpakko J, Kopra K, Hänninen P. Time-resolved fluorescence-based assay for rapid detection of *Escherichia coli*. Analytical Biochemistry. 2015;**470**:1-6.

[9] Martelet A, Lhostis G, Nevers MC, Volland H, Junot C, Becher F, et al. Phage amplification and immunomagnetic separation combined with targeted mass spectrometry for sensitive detection of viable bacteria in complex food matrices. Analytical Chemistry. 2015;**87**:5553-5560. DOI: 10.1021/

[10] Karoonuthaisiri N, Charlermroj R, Morton MJ, Oplatowska-Stachowiak M, Grant IR, Elliott CT. Development of a M13 bacteriophage-based SPR detection

using salmonella as a case study. Sensors and Actuators B: Chemical. 2014;**190**:214-220. DOI: 10.1016/j.

[11] Kong M, Shin JH, Heu S, Park JK, Ryu S. Lateral flow assay-based bacterial

detection using engineered cell wall binding domains of a phage endolysin. Biosensors & Bioelectronics.

2017;**96**:173-177. DOI: 10.1016/j.

[12] Farooq U, Yang Q, Ullah MW, Wang S. Bacterial biosensing: Recent advances in phage-based bioassays and biosensors. Biosensors & Bioelectronics.

2018;**118**:204-216. DOI: 10.1016/j.

Journal of Food Protection.

[13] Sharp NJ, Vandamm JP, Molineux IJ, Schofield DA. Rapid detection of bacillus anthracis in complex food matrices using phage-mediated bioluminescence.

10.1007/s00216-014-7985-3

DOI: 10.1016/j.ab.2014.09.002

ac504508a

snb.2013.08.068

bios.2017.05.010

bios.2018.07.058

*DOI: http://dx.doi.org/10.5772/intechopen.88644*

[1] Scharff RL. Economic burden from health losses due to foodborne illness in the United States. Journal of Food Protection. 2012;**75**:123-131. DOI: 10.4315/0362-028X.JFP-11-058

[2] Rohde A, Hammerl JA, Boone I, Jansen W, Fohler S, Klein G, et al. Overview of validated alternative methods for the detection of foodborne bacterial pathogens. Trends in Food Science and Technology. 2017;**62**:113-118.

DOI: 10.1016/J.TIFS.2017.02.006

[3] Yue H, He Y, Fan E, Wang L,

electrochemiluminescent biosensor for rapid and sensitive detection of pseudomonas aeruginosa using phage as highly specific recognition agent. Biosensors & Bioelectronics. 2017;**94**: 429-432. DOI: 10.1016/j.bios.2017.03.033

[4] Park MK, Li S, Chin BA. Detection of *Salmonella typhimurium* grown directly on tomato surface using phage-based magnetoelastic biosensors. Food and Bioprocess Technology. 2013;**6**:682-689.

DOI: 10.1007/s11947-011-0708-2

Hwang J, Oppenheim AB, Fekete RA, Giulian G, et al. High-sensitivity bacterial detection using biotintagged phage and quantum-dot nanocomplexes. Proceedings of the National Academy of Sciences. 2006;**103**:4841-4845. DOI: 10.1073/

[5] Edgar R, McKinstry M,

[6] Shabani A, Marquette CA,

[7] Burnham S, Hu J, Anany H, Brovko L, Deiss F, Derda R, et al. Towards rapid on-site phage-mediated detection of generic *Escherichia coli* in

Mandeville R, Lawrence MF. Magneticallyassisted impedimetric detection of bacteria using phage-modified carbon microarrays. Talanta. 2013;**116**:1047- 1053. DOI: 10.1016/j.talanta.2013.07.078

pnas.0601211103

Lu S, Fu Z. Label-free

**References**

*Applications of Phage-Based Biosensors in the Diagnosis of Infectious Diseases, Food Safety… DOI: http://dx.doi.org/10.5772/intechopen.88644*
