**8. Conclusion**

At present, the application scope of IVM technology can be extended to patients with various causes of infertility. In addition, the IVM technology is associated with acceptable pregnancy and live birth rates. Although IVM has been used as an effective treatment and achieved significant outcomes with thousands of healthy IVM babies having been delivered, IVM is still considered as an experimental technique by the society. With the development of IVM technology, the combination of natural cycle IVF with the IVM of immature oocytes can be used as an attractive regimen to promote IVM treatment. More infertile women can benefit from such approaches if the treatment process is simplified by mild stimulation, especially when the difficulty to obtain immature oocytes is reduced. Therefore, the combination of mild stimulation IVF and IVM treatment can become a viable alternative to current standard treatments. With the accumulation of more experience and results, it will be further demonstrated that the combination of mild stimulation IVF and IVM is not only a viable alternative to current standard treatments but may also become a potential option of first-line treatment.
