**3.1 Infant formula supplemented with probiotics**

European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Committee on Nutrition [19] published a systematic review of studies assessing the safety and health effects of probiotic-supplemented infant formulae. No conclusive data were obtained from ESPGHAN's analysis of infant and follow-on formulae due to considerable variability in the type and dose of probiotics used and supplementation periods.
