*7.5.4 Triptolide*

This is an immunosuppressive and anti-inflammatory agent that was extracted from an herb of Chinese origin (*Tripterygium wilfordii*). It decreases the expression of the NF-kB and genes related to inflammatory processes. This review chapter shows that this agent suppresses the expression of HBD2 induced by IL-1β in A549 cells and the suppression is associated with the inhibition of NF-kB [83].
