**1.3.2 Secondary liver cancer**

Malignant cells migrated from any tissues other than liver may invade hepatic tissue and develop neoplastic tumor in liver. This is described as secondary liver cancer. Spread of cancerous cells from outside the liver to the liver through blood flow or through the lymphatic system, the anchorage of the cells in liver, angiogenesis (formation of new blood vessels for supply of food and oxygen for new cells), and cellular proliferation leading to solid growth of mass are the possible sequences of secondary liver cancer. It is also called as metastatic cancer.
