**Meet the editor**

Rosana Pelayo obtained her Bachelors, Masters and Doctorate degrees from the National Autonomous University of Mexico and completed her postdoctoral fellowship at the Oklahoma Medical Research Foundation, in the Immunobiology and Cancer Program. Dr Pelayo is currently Senior Research Scientist and Principal Investigator in the Oncology Research Unit of the

Mexican Institute for Social Security, in Mexico City.

Contents

**Preface IX** 

Renata Binato

Rasmus Freter

**Part 1 Hematopoietic Stem Cell Properties 1** 

Eliana Abdelhay, Luciana Pizzatti and

Chapter 2 **Regulation of Hematopoietic Stem Cell Fate:** 

Yasushi Kubota and Shinya Kimura

Chapter 4 **Markers for Hematopoietic Stem Cells:** 

Takafumi Yokota, Kenji Oritani, Stefan Butz, Stephan Ewers,

Chapter 5 **Interferon Regulatory Factor-2 Regulates** 

Chapter 6 **Regulation of Tyrosine Kinase** 

Mayumi Naramura

Keiyo Takubo

Chapter 7 **The Hypoxia Regulatory System in** 

**Hematopoietic Stem Cells 133** 

Atsuko Masumi, Shoichiro Miyatake, Tomoko Kohno and Toshifumi Matsuyama

**Stem Cell Multipotency and Self-Renewal 3** 

**Self-Renewal, Quiescence and Survival 39** 

**Histories and Recent Achievements 77** 

Dietmar Vestweber and Yuzuru Kanakura

**Part 2 Regulation of Hematopoietic Stem Cells 89** 

Chapter 3 **Transcriptional Quiescence of Hematopoietic Stem Cells 61** 

**Hematopoietic Stem Cells in Mouse Bone Marrow 91** 

**Signaling by Cbl in Hematopoietic Stem Cells 113** 

Chapter 1 **Networks Establishing Hematopoietic** 
