Contents


**Chapter 6 129** Stem Cells and Extracellular Vesicles: Biological Regulators of Physiology and Disease *by Theo Borgovan, Lorin Crawford, Chibuikem Nwizu and Peter Quesenberry*

Preface

In recent years, progress in cell biology has uncovered complex molecular networks that have elucidated the underpinning defects and therapeutic targets in biological systems. Advances in molecular biology and the pathology of disease have provided the foundation for the advent of therapeutic interventions and innovations designed to prevent or modify disease. Today, personalized medicine is delivering targeted therapies that are optimized for the patient's phenotype and

As our understanding of the broad field of "omics" manifested by genomics, transcriptomics, proteomics, and metabolomics has contributed significantly to twenty-first century therapeutics, so too has our understanding of fundamental cell biology. To that end, it became apparent that a need exists for capturing advances in

The dawn of cell therapies and medicines is captured in this new and exciting book entitled *Innovation in Cell Research and Therapy*. This book provides an in-depth description of some of the key issues and advancements in cell biology and its application to novel therapeutic approaches. Six chapters authored by experts in the field address the components of cells, cell structure, and the emergence of stem cells and their applications. The chapters provide state-of-the-art descriptions and summaries and identify the future needs in this continuously evolving field. This book is meant to raise awareness of the complexity associated with defining and characterizing the biological and pharmacological properties of cell therapy

Hardly a day passes without hearing of a biomedical advance. Innovation in the biosciences has progressed at a rapid speed. Given that, why should you read this book? What do we bring to the table? Our answer is that we are a unique team of global experts that come from diverse backgrounds. In this engaging book we deliver a comprehensive compendium of some of the most fundamental, important, and enabling advances in cell biology. As you read the book you will personally engage with leaders in the cell biology field. I am confident that your knowledge and insight into cell biology will be significantly impacted. Indeed, the dawn of cell therapies and medicines is captured in this new and

I am humbled and most gratified to IntechOpen for inviting me to serve as editor of this work. My sincere thanks go to Josip Knapic, Author Service Manager, and Martina Usljebrka, Commissioning Editor, for all of their help and assistance throughout the entire process. I thank my colleagues at the Touro College of Pharmacy and New York Medical College for fostering an inspiring environment with a shared quest for biomedical advancements. Words cannot express my gratitude to my wife Brenda and our children and grandchildren for their constant support and encouragement. This book is dedicated to the memory of my wonderful

genotype.

modalities.

exciting book.

cell structure, function, and therapy.
