Meet the editor

Assoc. Prof. Dr. Anil Tombak, MD, was born on April 25, 1976. He graduated from Gazi Anatolian High School in 1994 and then from Çukurova University Medical Faculty in 2000. Subsequently, he was trained at Mersin University Medical Faculty, Internal Medicine Department, and after internal medicine specialization, he became a Fellow of Hematology at the same University. He became a hematologist in 2013 and is still working at Mersin

University Medical Faculty, Department of Internal Medicine-Hematology, Mersin, Turkey. He has performed research in several fields, with over 50 publications in (inter)national journals and numerous papers at scientific conferences. He received several awards and is a member of the Turkish Society of Hematology. Dr. Tombak is married and has two children.

Contents

**Section 1**

*by Anil Tombak*

*by Soumya Das*

*and Oksana Gusyakova*

**Section 2**

Blood Transfusion Reactions *by John Ayodele Olaniyi*

Hemolytic Disease of the Fetus and Newborn

Fetal RhD Status via Biosensor Technology

**Preface III**

Clinical Significance of Blood Groups **1**

**Chapter 1 3**

**Chapter 2 7**

**Chapter 3 25**

Future Perspectives **49**

**Chapter 4 51**

**Chapter 5 63** ABO Blood Group Antigens as a Model of Studying Protein-Protein Interactions *by Frida N. Gylmiyarova, Elena Ryskina, Nataliya Kolotyeva, Valeriia Kuzmicheva* 

A New Alternative Approach for RhD Incompatibility; Determination

*by Ebru Dündar Yenilmez, Umut Kökbaş and Abdullah Tuli*

Introductory Chapter: Blood Groups - From Past to the Future

## Contents


*by Frida N. Gylmiyarova, Elena Ryskina, Nataliya Kolotyeva, Valeriia Kuzmicheva and Oksana Gusyakova* 

Preface

Today, information in medical science is increasing rapidly, and with the communication age, accessing information is quite easy. However, with this increasing knowledge, information complexity has emerged. Thus, despite all this increasing knowledge, the interest and need for basic books have not diminished. Blood groups, erythrocyte antigens, and transfusion are fundamental areas of medicine and are related to many disciplines of science like hematology, immunology, surgery, and genetics. This book is a collection of current information related to blood groups and transfusion, and a practical resource for all concerned physicians.

I would like to thank all the authors and IntechOpen and hope that this book will be a stepping stone for scientists who are rapidly advancing their science journey.

> **Dr. Anil Tombak, MD** Associate Professor,

> > Mersin, Turkey

Department of Internal Medicine-Hematology,

Mersin University Medical Faculty,
