**3. Conclusion**

Analysis of the circadian rhythm of the peripheral and central blood pressure revealed gender-related features of the diurnal SBP and DBP profiles—the decrease of the degree of nocturnal decline in brachial and aortic pressure with age in healthy boys and the absence of such changes in girls 12–17 years old. The tendency to decrease with age of the degree of nocturnal dip in peripheral pressure in young men indicates the peculiarities of the age dynamics of the formation of the circadian organization of the vegetative mechanisms of regulation of the vascular wall stiffness that underlie the formation of daily arterial pressure profile. The circadian rhythm of brachial and aortic diastolic pressure in adolescents was characterized by a shift of the 25–75 percentile ranges toward higher levels of the degree of nocturnal dip in DBP compared to that for the SBP (14–23 and 9–15%, respectively). This could be probably due to the different contribution of the vasomotor component to the formation of circadian fluctuations of systolic and diastolic pressures. In addition, the values of 95 percentile, by which the disturbance of the arterial blood pressure profile is pronounced, were 28–29% for brachial and aortic diastolic pressures, which exceeds the generally accepted standard values for the adult population (22%). Thus it is necessary to provide more studies on mechanisms that underline the differences. The obtained data can be used to improve accuracy when decoding data of ABPM and interpretation of the results obtained in adolescents.
