**3. Putative neuroplastic mechanisms of psychotherapy**

Although studies of neural parameters of therapeutic change under psychotherapy are under-represented relative to analogous studies of medications, emerging literature support the thesis that changes in affect, cognition and behavior mediated by psychotherapy have demonstrable neuroplastic underpinnings. Since the call for more neuroscientifically informed approaches to psychotherapy [44], studies have elucidated neural mechanism of psychotherapy-induced changes in brain activity profiles across a range of psychiatric disorders.
