2.1 Overview of the computer-aided diagnosis system

A computer-aided diagnosis (CAD) (see Figure 1) system consists in different important stages including image acquisition and preprocessing, feature extraction, feature selection, and classification.

In this chapter, the described CAD system focuses on 18F-FDG-PET images from local and public databases and is atlas-based. This means that each PET brain image is mapped into anatomical volume of interests (VOIs), on which features are extracted and then input to a classifier, instead of inputting the whole voxels of each brain image. The goal of such a system is to provide doctors with tools that help them to classify AD and HC subjects.

Alzheimer's Disease Computer-Aided Diagnosis on Positron Emission Tomography Brain Images… DOI: http://dx.doi.org/10.5772/intechopen.86114
