2. Conclusion

After highs and lows in scientific output on brain connectivity in recent years, the technological advances in neuroimaging have revolutionized the knowledge on mechanisms of neural networks, and this fact represents a major milestone for the multidisciplinarity of neuroscience.

From a clinical standpoint, the illustrative cases reporting syndromes of disconnection to the frontal lobe cited in this chapter exemplify the pressing need for future studies to elucidate the physiopathogenic process of different classic neuropsychiatric syndromes. These studies may gradually oppose the localizationist view of brain functioning. Based on the data available in the literature, this knowledge will likely have growing impact in the academic setting and become increasingly important in the interface among different areas such as neurology, neurosurgery, and psychiatry.
