**2.2. Bacteraemia and septicaemia**

aminoglycoside (tobramycin) and vancomycin or linezolid, to cover MRSA. If a *Legionella* infection is suspected, a macrolide (azithromycin) must also be associated [7] (**Table 1**).

**Table 1.** Empirical antibiotic treatment of HAP with MDRO.

**Figure 1.** Antibiotic therapy in HAP.

18 Current Topics in Intensive Care Medicine

The duration of the antibiotic treatment in HAP must be adjusted to the severity of the disease, the time required to obtain clinical improvement and the aetiological agent, but it has to exceed with at least 3 days the time to clinical improvement. The clinical response occurs after
