**Meet the editor**

Guy-Joseph Lemamy, PhD, is currently a professor in the Department of Cellular and Molecular Biology-Genetics, and Director of the Laboratory of Cellular and Molecular Biopathologies, at the Faculty of Medicine, Université des Sciences de la Santé (USS), Libreville, Gabon. Dr. Lemamy obtained his PhD in Biochemistry and Cell Biology at the Faculty of Medicine, Université

Montpellier 1, France. His PhD thesis work concerned the search for new tumor markers in breast cancers, led by the Medical Research Institute (INSERM U148) in Montpellier, France. Dr. Lemamy is the author of many book chapters and journal articles about tumor markers and is involved in other scientific activities, such as membership of the Scientific Advisory Board of Gabon Scientific Research Guiding Plan.

Contents

**Preface VII**

Guy Joseph Lemamy

**Section 2 Molecular Markers Studies 9**

Pandurangan Ramaraj

Chapter 1 **Introductory Chapter: Genes Expression in the Control of Cell Cycle and Their Potential Value in Cancer Prognosis 3**

Chapter 2 **The Human Epidermal Growth Factor Receptor 2 (HER2) as a**

**HER2 Activation and Diagnostic Implications 11**

Chapter 4 **CBX4 Expression and AFB1-Related Liver Cancer Prognosis 51**

Qun-Ying Su, Jun Lu, Xiao-Ying Huang, Jin-Guang Yao, Xue-Min Wu, Bing-Chen Huang, Chao Wang, Qiang Xia and Xi-Dai Long

Chapter 3 **Is Melanoma a Hormone-Dependent Cancer or a Hormone-Responsive Cancer? 33**

**Section 3 Prognosis and Diagnosis Factors Studies 49**

**Prognostic and Predictive Biomarker: Molecular Insights into**

Daniela Furrer, Claudie Paquet, Simon Jacob and Caroline Diorio

**Section 1 Introduction 1**

## Contents



**Section 1**

**Introduction**

**Section 1** 
