**4. Challenges in analytical methods for chalcogen compounds and materials**

Natural chalcogen compounds which are present in certain matrix in perfect blends, and separation procedure must be conducted first, followed by purification prior to analysis. There are several parameters must be taken into account for the correctness of measurements. In the extraction of sulfur-containing compounds in plants, one would normally use phytochemical procedures [44] by considering the separation of constituent analytes according to the similarities of the compounds.

The development of new materials from chalcogen compounds due to the functionality of the materials must be supported by a better analytical methodology. When materials are dedicated to a specific purpose, then the proof to that claim might be assigned analytically too. In this case, there are two types of analytical chemistry for the assignment of chalcogen materials. In short, the need of analytical method can cover four types of analysis:


All of the human efforts in the laboratory as well as in computational analysis are based on the four types of analytical objectives listed above. The emphasis must depend on the purpose or in one segment of a longer process and all point of views can count. Therefore, any bigger steps can be started from chemistry discussion and developed into a wider investigation perspective.
