**6. Epidermal carcinoma**

It is the most common malignant neoplasm of the oral cavity, corresponding to 95% of the tumors of the patients, of form. We highlight the growing prevalence of HIV/AIDS patients. According to the National Institute of Cancer (INCA)/Ministry of Health (MS), the estimate for 2018, regarding the number of cases of oral cancer in general in Brazil, is 14,700 new cases, considering the region as the seventh most frequently affected by malignant tumors in the Brazilian population.

Clinical features include ulcerated superficial, endophytic lesions (infiltrative ulcer and destructive ulcer), exophytic lesions (moriform vegetative, papilliferous vegetative and cauliflower vegetation), nodular (sub mucosa and deep) lesions. The most common clinical feature of squamous cell carcinoma is chronic ulcer. Due to this ulcerated clinical aspect, often granulomatous, we must associate in the differential diagnosis ulcerated lesions of long duration of infectious diseases such as tuberculosis, syphilis, histoplasmosis and paracoccidioidomycosis [20, 21].

Its prevalence and incidence is greatest in individuals over 40 years of age, smokers and alcoholics. The male gender is more affected than the female in the proportion of 3:1.
