*Edited by Houria Bachtarzi*

Ongoing advances in pharmaceutical biotechnology have paved the way to groundbreaking new biological therapeutic modalities, offering the possibility of a durable curative approach for a number of life-threatening diseases, for which the medical need is as yet unmet. Over the past decades, gene therapy has seen a massive transformation from a proofof-concept approach to a clinical reality culminating in the regulatory approval of state-of-the-art products in the European Union and in the United States. This book captures some of the scientific progresses notably in gene transfer technologies and translational development of *in vivo* and *ex vivo* gene therapy interventions in the treatment of a broad range of complex and debilitating noninherited and inherited disorders such as: human immunodeficiency virus 1 (HIV-1) infection, cancer, cystic fibrosis, hereditary retinopathies, haemophilia B, cardiac diseases, and chronic liver fibrosis.

ISBN 978-1-78985-717-7

*In Vivo*

and *Ex Vivo*

Gene Therapy for Inherited and Non-Inherited Disorders

Published in London, UK © 2019 IntechOpen © vchal / iStock
