**Meet the editors**

Ming-Kung Yeh gained his Bachelor and Master degrees from the National Defense Medical Center, Taiwan in 1986 and 1988, respectively. He completed his PhD at the University of Nottingham, UK, in 1996. From 1988 to 2008, he worked in the Tri-Service General Hospital, Taiwan from a basic pharmacist to a chief pharmacist and became a Professor of Preventive Medicine in 2008. He

was the Head of the Pharmaceutical Administration, Ministry of National Defense, Taiwan, from 2011 to 2013. He was the General Director of the Taiwan Food and Drug Administration (TFDA), Ministry of Health and Welfare (MOHW) from 2013 to 2014, and a superintendent in MOHW from 2014 to 2016. His research focuses on public food and drug safety, and he also takes an active interest in pharmacy education, practice, and policy. Currently, he is devoting himself to developing cell therapy products.

Yuan-Chuan Chen completed his PhD in Biochemistry at the University of California, Berkeley, USA, in 2015 and had postdoctoral studies at the Taiwan Food and Drug Administration (TFDA) from 2015 to 2016. His research interests include pharmacy, biochemistry, microbiology/ virology, cell/molecule biology, biotechnology/nanotechnology, cell /gene therapy, and policy/regulation. His

studies focus on the discovery, production, application, perspectives, and challenges of biopharmaceuticals. Additionally, he is interested in basic research, the development of agricultural/industrial products, and human therapeutics using the CRISPR/Cas9 system.

Contents

**Preface VII**

Chapter 1 **Introductory Chapter: Biopharmaceuticals 3** Yuan-Chuan Chen and Ming-Kung Yeh

Chapter 2 **Characterization of Biopharmaceuticals Focusing on Antibody**

Woojeong Kim, Kui Hyun Kang and Jung-Keun Suh

Chapter 3 **"Cell-Free Therapeutics" from Components Secreted by Mesenchymal Stromal Cells as a Novel Class of**

I. Makarevich and Anastasia Yu. Efimenko

Chapter 4 **Impact of Immunotherapy in the Treatment of**

Georgy D. Sagaradze, Peter P. Nimiritsky, Zhanna A. Akopyan, Pavel

Jessica Silva, Ana Miranda, João Sousa, Alberto Pais and Carla

**Section 1 Background 1**

**Section 2 Characteristic 13**

**Section 3 Development 45**

**Section 4 Application 63**

Vitorino

**Therapeutics 15**

**Biopharmaceuticals 47**

**Glioblastoma 65**
