**Conflict of interest**

**5. Conclusions**

164 Advances in Extra-corporeal Perfusion Therapies

and priming volume

The optimisation of ECC management through:

• Accurate control of the patient's hemodilution

system provided with four roller pumps is 33 kg.

this concept of McECC and holder system.

gery were carried out with this ECC concept.

**6. Future goals**

flow and venous flow).

ing to the needs of the users.

• Used techniques (cardioplegia, autotransfusion system, etc.)

dynamic, safe and accurate monitoring, security, etc.)

• Optimal choice of material (VAVD system, HSVR, surface coating, cannulas, design, hemo-

• The reduction of contact area surface of air/blood, blood/materials, dead space of the circuit

It has a direct impact on postoperative patients who have undergone surgical intervention

For 23 years, this strategy of developing the McECC and the CPB console with the Holder System, the circuit, the various components that constitute the ECC allowed us to operate all types of patients with various pathologies with a safe and versatile system that is adapted to each patient. It gave us the possibility of a different approach for fragile patients or having to

The CPB HL30 console is very stable; thanks to its concept with its center of gravity which is low, it allowed us to place the Holder system away from the CPB console without having any technical problems. The assembly is very safe and flexible, the weight of the overall holder

For 11 years, we have realised more than 3600 cardio-thoracic surgeries in our hospital with

This holder system was placed in 2009 on two CPB consoles at the Azienda Ospedaliera Universitaria "Ospedali Riuniti In Trieste, Italy, where more than 4300 cardio-vascular sur-

Create a VAVD system with a servo controller to monitor the different pressures in HSVR (positive and negative) with respect to the hemodynamics of the patient and the ECC (arterial

Reduce the contact surface of the blood with air and biomaterials caused by HSVR, by creation of a safe and versatile VAVD HSVR that can be used as a closed or open system accord-

• Hemodynamic equilibrium of the patient and ECC (arterial and venous flow)

under ECC; it could be comparable to an artificial reduction of ECC time.

undergo paediatric, valvular or minimally invasive heart surgery.

The authors declare that they have no conflicts of interest.
