**8. Atherogenic dyslipidemia**

In atherogenic dyslipidemia which is the result of an increase in triglyceride levels, triglyceride content is increased. The primary source of triglycerides is the VLDL. While LDL molecules are more easily oxidized, HDL molecules are more easily eliminated from the kidneys. Metabolic syndrome, type 2 diabetes, insulin resistance, abdominal obesity, and polycystic ovary syndrome are associated with atherogenic dyslipidemia.

In the case of atherogenic dyslipidemia, since chylomicrons have no effect on atherosclerosis, non-HDL cholesterol level is used rather than triglyceride level. Although levels of LDL, VLDL, and chylomicron residues can be determined by detecting Apo B levels, there is limited access and standardization for the detection of Apo B level. In the ESC dyslipidemia guide, non-HDL cholesterol calculation is recommended instead of measuring ApoB levels in the presence of hypertriglyceridemia. (Class 2a) In a study conducted by Puri et al., the level of non-HDL cholesterol rather than LDL cholesterol significantly correlated with atheromatous progression when the triglyceride level rises above 200 mg/dl. In the NICE guideline, all individuals are focused on evaluating non-HDL cholesterol exclusively from LDL cholesterol.
