**3. Lipoprotein structure**

The lipid core that carries triglycerides and cholesterol esters has a hydrophobic structure and is coated with polar capsules which contain apolipoproteins, phospholipids, and nonesterified cholesterol crystals. When the lipoproteins were classified according to their migration rates in lipoprotein electrophoresis, the band closest to the origin formed the chylomicron band; low-density lipoprotein (LDL) in the beta band, very-low-density lipoproteins (VLDL) in the pre-beta band, and high-density lipoprotein (HDL) in the alpha band, respectively.

Chylomicron is synthesized in liver from dietary fat molecules. Since chylomicrons and VLDL molecules larger than 70 nanometers cannot reach the subintimal region through the transcytotic transport system, chylomicrons do not have atherogenic potential. But chylomicron remnants are atherogenic and cannot be removed from circulation when they are present in high quantities [3]. Hydrolysis of the chylomicrons with lipoprotein lipase results in the formation of VLDL. The majority of VLDL is converted to LDL. Chylomicrons are attached to ApoB48. Chylomicron remnants, LDL, and VLDL are connected to apoB100 and are called non-HDL cholesterol.
