**7. Lipoprotein (a)**

Lipoprotein (a) (Lp (a)) consists of an LDL molecule bound to apolipoprotein (a). Lipoprotein (a) is structurally similar to plasminogen and is thought to play a role in atherothrombosis with antifibrinolytic properties. In a study with patients with normal LDL and elevated Lp(a) levels, it was determined that increased Lp(a) levels was associated with high cardiovascular risk [17].

Cholesterol ester transfer protein (CETP) is responsible for transferring cholesterol esters. CETP inhibitors are associated with increased HDL and decreased LDL levels. In the study conducted with anacetrapib, there was no significant difference in mortality despite a significant increase in HDL and a significant decrease in non-HDL cholesterol compared to placebo [18].
