**12. Conclusion**

Isolated pancreatic metastases suitable for resection are rare eventualities; the renal cell carcinoma origin being the most frequently reported situations. When diagnosed as metachronous isolated lesions, such metastases can be submitted to surgery with curative intent, long-term survival rates being reported. Another primary with good outcomes after pancreatic resections for metastatic disease is represented by ovarian cancer, debulking surgery to no residual disease including pancreatic resections being associated with long-term survival. When it comes to the other origins, the reported results are inconstant and no standard therapeutic protocol can be established due to the paucity of cases. However, it seems that the best outcomes should be expected in cases diagnosed with isolated metachronous lesions with long disease free survival intervals and in the absence of extrapancreatic disease. In such cases, association of surgery as part of multidisciplinary approach might improve the long-term outcomes.

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