**10. Pancreatic metastases from lung cancer**

Lung cancer is associated with the highest mortality rates, being associated most often with liver, brain, bone or lymph node metastases [60].

Pancreatic metastases from lung cancer are not a usual condition; in a review of 333 cases diagnosed with pancreatic metastases, the most common origin of the pancreatic lesions was represented by the renal cell carcinomas, being responsive for 45% of cases; among the remaining cases, the lung was reported as the origin of the pancreatic metastases in 14.7% of cases [61].

When it comes to the most common histopathological subtype of lung cancer which might induce the apparition of pancreatic lesions, small cell lung cancer has been most often reported; other incriminated histopathological subtypes included large cell carcinomas, squamous cell carcinomas and anaplastic bronchial carcinomas [62].

When diagnosed, pancreatic metastases from lung cancer are usually encountered as part of the systemic recurrence, with metachronous character; therefore the patient will be a candidate for palliative oncologic treatment, with low rates of long-term survival. Oligometastatic pancreatic disease with lung cancer origin appears in rare situations and it seem to be best treated through surgery with curative intent; however, the longterm outcomes failed to demonstrate good survival rates, the median overall survival ranging from a few months to a few years [10] due to biological aggressiveness of the primary tumor.
