**3. Insulin-resistance and BPH**

The main function of insulin includes regulation of glucose uptake, glycogenesis and tight control of the plasma glucose level (Vikram and Jena, 2010). Insulin-resistance is a condition in which normal level of insulin elicits subnormal response. It is a condition which is associated with a group of disorders such as obesity, dyslipidemia, elevated fasting glucose level, hyperinsulinemia and hypertension. In addition to the type 2 diabetes and cardiovascular diseases, patients with insulin-resistance syndrome are at higher risk of BPH (Kasturi et al., 2006). Possible implications of the diabetes, insulin-resistance and insulinresistance associated disorders in the pathogenesis of BPH have been previously reviewed, and interested readers are encouraged to read the concerned articles for more information (Vikram et al., 2010a; Wang and Olumi, 2011)**.**
