**2.2 Randomized controlled trial (RCT)**

Large-scale, randomized, controlled clinical trials of fenofibrate involving type II DM, that is, high-risk patients for arteriosclerosis, were conducted. The representative 3 studies were reviewed in this section: "DAIS" study, regarding coronary arteriosclerosis retraction, "FIELD" study, in which the inhibitory effects on cardiovascular events were examined, and "ACCORD" study, in which the inhibitory effects of lipid-intensified therapy with statins on cardiovascular events were investigated.
