**4.2.1 Non-pharmacologic therapy**

The non-pharmacologic therapy should be first applied to all patients with hypertriglyceridemia, through modification of lifestyle; diet should be instituted to reduce fat intake, weight reduction, reduction or elimination of alcohol intake, smoking cessation control of hyperglycemia and diabetes with insulin sensitizers such as metformin. In studies, it has been found that diets associated with exercise and resistance training promotes decrease of 21% and 27%, respectively, TG levels in HIV-infected patients (Henry et al., 1998; Yarashesky et al., 2001).

Patients who demonstrate extreme elevations in TG level (> 1000 mg / dL) and with a history of pancreatitis should be treated associating pharmacologic and non-pharmacologic therapy (Dube et al., 2003).
