**Preface XIII**


Alyssa Green, Peter G. Thomas, Rebecca Wilde-Onia, Scott J. Kohler, Joan D. Sweeney, Deborah M. Stahlnecker and Stanislaw P. Stawicki



Chapter 18 **Diagnosis, Treatment, and Outcomes of Antibody-Mediated Rejection in Kidney Transplantation 375** Vasishta S. Tatapudi and Bonnie E. Lonze

Chapter 20 **Metabolic Drug Interactions with Immunosuppressants 409**

Seema Naik, Hong Zheng, Kevin Rakszawski, Clare Sample, Jeff

Contents **VII**

Chapter 19 **Clinical and Pathological Review of Post Transplant Lymphoproliferative Disorders 395**

Sample and Michael Bayerl

Katalin Monostory

Chapter 18 **Diagnosis, Treatment, and Outcomes of Antibody-Mediated Rejection in Kidney Transplantation 375** Vasishta S. Tatapudi and Bonnie E. Lonze

Chapter 8 **Experimental Brain Death Models in Liver**

Jiménez-Castro and Carmen Peralta

Chapter 9 **Pancreas Retrieval for Whole Organ and Islet Cell**

Maria Eugenia Cornide-Petronio, Araní Casillas-Ramírez, Mónica B.

Pedro Ventura-Aguiar, Joana Ferrer-Fábrega and Maria José Ricart

Jorge Andrade-Sierra, Pedro Alejandro Vazquez-Galvan, Hernesto Hernandez-Reyes, Lydia A. Mercado-Jáuregui, Jonathan S. Chávez-Iñiguez, Eduardo González-Espinoza, Benjamin Gómez-Navarro

Wayne J. Hawthorne, Ahmer Hameed and Henry Pleass

Chapter 10 **Organ Donation Course in Medical Education Program 187** Nilufer Yılmaz, Sibel Demiral and Taylan Özgür Sezer

Chapter 12 **Anesthetic Considerations in Transplant Recipients for**

Katarina Tomulić Brusich and Ivana Acan

Chapter 15 **Cardiovascular Diseases in Patients with Renal**

Daniela Loncar and Selma Hodzic

Chapter 17 **Immunosuppressive Minimization Strategies in Kidney**

**Transplantation 135**

**VI** Contents

**Transplantation 153**

Chapter 11 **Anesthesia for Liver Transplantation 209** Gabriela Droc and Lavinia Jipa

**Nontransplant Surgery 229**

Chapter 13 **Pancreas Transplantation 259**

Chapter 14 **Intestinal Transplantation 289** Georgios Vrakas

**Transplantation 313**

**Transplantation 353**

and José I. Cerrillos-Gutiérrez

Chapter 16 **Xenotransplantation 331** Sean Stevens

**Section 2 Transplantation 207**


Preface

pancreas, and small intestine.

progress in the field of tolerance.

est in transplantation, improving the lives of their patients.

One of the most interesting and at the same time most challenging fields of medicine and surgery has been that of organ donation and transplantation. It is a field that has made tre‐ mendous strides during the last few decades through the combined input and efforts of sci‐ entists from various specialties including surgeons, hepatologists, nephrologists, immunologists, ethicists, and infectious disease specialists. What started as a dream of pio‐ neers has become a reality for the thousands of our patients whose lives can now be saved and improved. However, at the same time, the challenges remain significant and so do the expectations, for what was once an experimental treatment could eventually become the fu‐ ture of medicine, as it involves most organs including the heart, lungs, eyes, liver, kidney,

This book with the contribution of an excellent group of world authorities in the field of organ donation and transplantation presents the challenges involved including the ethical, legal, and medical issues in organ donation and the technical and immunological problems facing experts involved in the care of these patients. In addition to the knowledge shared, the authors provide their personal clinical experience making this book an extremely useful tool for every scientist and physician practicing in the field of transplantation. The book is divided into a section dealing with donation-related issues and challenges and another one where the different types of transplantation are presented. The chapters include information on the current state and different types of donation, the challenges identified in increasing donation, and the potential solutions. Chapters in both the organ donation and the trans‐ plantation section provide us with a combination of the technical and surgical aspects, as well as a glimpse of the opportunities offered by molecular and basic science in achieving

We can learn from the history of transplantation and, at the same time, tackle the remaining critical questions, such as achieving tolerance, which represents the Holy Grail of medicine. Overall, this book represents a true tour-de-force of a variety of topics having to do with organ donation and transplantation. It should be stressed that the intended audience are sci‐ entists, physicians and surgeons of different specialties, which all have in common an inter‐

**Georgios Tsoulfas, MD, PhD, FICS, FACS**

Associate Professor of Surgery Aristotle University of Thessaloniki

Thessaloniki, Greece
