**4. Conclusion**

Glioma surgery is one of the most impacting surgical interventions to human health, life, and quality of it. As the molecular knowledge of the life circle of gliomas and techniques improves, it increases our dream that potential curing glioma will come true. Today, the most important treatment option for preserving the quality of life and overall survival is surgical resection. If possible, maximal surgical resection with preservation of neurological functions should be first option in treatment of low and high grade glioma. The resection should be performed with the balance of maximal resection and maximal preservation or improvement of the quality of life. The new promising approach in glioma surgery is supratotal resection with the use of electrostimulation mapping, which makes glioma surgery an individual treatment option for each single patient. But there is a need of more clinical evidence to make supratotal resection widely used. Supratotal resection today is still reserved for individual cases. However, if it is impossible to perform GTR, then STR should be performed. Glioma biopsy is only the last option to confirm the diagnosis for gliomas without possible surgical resection as treatment option.
