**Meet the editors**

Ibrahim Omerhodžić is a consultant neurosurgeon at the Department of Neurosurgery, Clinical Center University of Sarajevo. He specializes in brain tumor surgery, in both adults and children, but also performs cerebrovascular and spine surgeries on a daily basis. His clinical and teaching efforts are focused on perfect-

ing surgical techniques for young neurosurgeons and residents in his group and for establishing a contemporary educational training program. He is a prominent member of the Bosnian-Herzegovinian American Academy of Arts and Sciences and an active member of the World Academy of Neurological Surgery.

Kenan Arnautović is Professor of Neurosurgery, Department of Neurosurgery, University of Tennessee, Attending Neurosurgeon at Semmes-Murphey Neurologic and Spine Institute, and Chairman, Baptist Neuroscience Institute, Baptist Memorial Hospital, Memphis, TN, USA. Dr. Arnautovic has published extensively in neurosur-

gery. His special interests include neurooncology, skull base neurosurgery, complex spine surgery, general neurosurgery, pituitary tumor and Chiari malformation surgery.

Contents

**Preface VII**

**Diagnosis 1** Ibrahim Omerhodžić

**Glioma's Case 13**

**Glioblastoma 31**

Ponce de León

Gao, Jun Su and Huan Ren

Seyfried

Chapter 1 **Introductory Chapter: Glioma - Merciless Medical**

Chapter 2 **Functional and Therapeutic Implications of Mitochondrial**

Chapter 3 **Receptor Tyrosine Kinase Interaction with the Tumor**

Chapter 4 **Astrocytomas and miRNAs: Are They Useful? 57**

**TRPM7 Blockade in Glioblastoma IV 81**

Michael Georgieff and E. Marion Schneider

**Diagnosis and Management 95** Ștefan Ioan Florian and Sergiu Șuşman

Chapter 5 **Mitophagy-Related Cell Death Mediated by Vacquinol-1 and**

Chapter 6 **Diffuse Astrocytoma and Oligodendroglioma: An Integrated**

Philip Sander, Paul Walther, Barbara Moepps, Michael Hinz, Haouraa Mostafa, Patrick Schaefer, Andrej Pala, C. Rainer Wirtz,

**Network and Mitochondria-Associated Membranes: The**

**Microenvironment in Malignant Progression of Human**

Gabriel Arismendi-Morillo, Alan Castellano-Ramírez and Thomas N.

Yujiao Gong, Yucui Dong, Jingru Cui, Quanye Sun, Ziqi Zhen, Yifan

Mario Perezpeña-Diazconti, Pilar Eguía-Aguilar and Fernando Chico
