**7. Alteration of receptor functionality**

The neurons communicate with other neuronal cells through neurotransmitters. The neurotransmitters are released from presynaptic boutons to the postsynaptic compartments which are recognized by receptor. The neuronal receptors are classified as inhibitory and excitatory, and for this reason different effects are observed in neuron functionality. Mutation or alteration of neurotransmitters affects receptor functionality and neurodegenerative effect.
