5. Forskolin (Coleus forskohlii)

Estimation of complete blood count (CBC) such as determination of different hematological parameters, such as red blood cells (RBC), white blood cells (WBCs), hemoglobin (HB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), neutrophils%, lymphocytes%, monocytes%, eosinophil's%, basophils%, mean platelet volume (MPV), platelet distribution width (PDW)%, plateletcrit (PCT)% and platelets (PLTs) was

Figure 3. Proposed experimental design: propionic acid-induced behavioral and biochemical estimations.

Estimation of blood glucose levels, triglycerides levels, total cholesterol levels, serum C-reactive

9. Inflammatory parameters in tissue homogenate-enzyme-linked immunosorbent assay (ELISA)

Phytochemicals drugs have been used since ancient times as medicines for treatment of a range of diseases. Medicinal plants have played a key role in world health. In spite of the great

Estimation of TNF-α, interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10)

measured in rat serum or blood sample

10 Recent Advances in Neurodegeneration

10. Estimation of biochemical parameters in urine

11. Histopathological and morphological sections studies

4. Future perspectives and treatment approach

Urine output, urine dipstick test

12. Immunohistochemistry

8. Miscellaneous

protein (CRP) levels

Coleus forskohlii known as phashana bedi (Telugu) a medicinal plant found in the Indian subcontinent is widely used in the Indian system of medicine. Forskolin (FSK) (also known as Colonels) is labdane diterpene that is obtained from the tuberous roots of Coleus forskohlii, which belongs to the family of Lamiaceae. Coleus Forskohlii is one of the world's most researched plant in which FSK is believed to be the plant's most active constituent. C. forskohlii has been used as an important folk medicine in India. C. forskohlii is a perennial herb and grows wild in arid and semi-arid regions of India, Nepal and Thailand; the roots have long been used in Ayurvedic medicine [50]. In traditional medicine, C. forskohlii is commonly used in different countries for various health disorders including cardiovascular diseases, hypertension, asthma, glaucoma and Alzheimer's disease. Its further use in promoting lean body mass, treating mood disorders and its anticancer activities is well known.
