**6. Conclusion**

Malaysian tropical rainforests comprise a wide range of medicinal plants that have been screened for their secondary metabolites and potential biological and therapeutic effects. Selected plant species from the agriculture NKEA-EPP1 demonstrated numerous pharmacological activities which were attributed to the presence of biologically active secondary metabolites, namely, flavonoids, quassinoids, phytosterols, and terpenoids. The use of local plants toward combating the country's high-prevalent disease such as dengue could be further explored. While a lot of effort has been put in, further research and development into plant secondary metabolites are needed including using the plant tissue culture approach toward reaching high-value herbal industry.

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