**2. Therapeutic applications of placenta mesenchymal stromal cells (PMSC) in preclinical models**

Stem cell therapies are expected to provide substantial benefits to patients suffering a wide range of pathologies. The plasticity and pleiotropic properties of PMSC that include immunomodulation and inflammation control, angiogenesis, neuroprotection, and antiapoptosis, among others, have been widely evaluated at the preclinical level [9, 46, 47].
