**2.11. Statistical analysis**

Statistical analysis was performed using GraphPad Prism 6 software (La Jolla, CA, USA). The data shown represent the mean ± standard error of the mean (SEM). Comparisons of HD-BMMSC with MM-BMMSC were performed using the Mann-Whitney *U* test. The Wilcoxon signed-rank test was used for the analysis of co-cultures. Results were considered statistically significant when *p* ≤ 0.05.
