**Author details**

Flavia Alejandra Bruna1,2\*

\*Address all correspondence to: flabruna@gmail.com

1 Instituto de Biología y Medicina Experimental de Cuyo, Technological Scientific Center CONICET, Mendoza, Argentina

[5] Maggini J, Mirkin G, Bognanni I, Holmberg J, Piazzón IM, Nepomnaschy I, Costa H, Cañones C, Raiden S, Vermeulen M. Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile. PLoS One. 2010;**5**:e9252 [6] Pendleton C, Li Q, Chesler DA, Yuan K, Guerrero-Cazares H, Quinones-Hinojosa A. Mesenchymal stem cells derived from adipose tissue vs bone marrow: In vitro compari-

Multipotent Stromal Cells in a Tumor Microenvironment http://dx.doi.org/10.5772/intechopen.77345 77

[7] Raghuvanshi S, Sharma P, Singh S, Van Kaer L, Das G. Mycobacterium tuberculosis evades host immunity by recruiting mesenchymal stem cells. Proceedings of the

[8] Yoo KH, Jang IK, Lee MW, Kim HE, Yang MS, Eom Y, Lee JE, Kim YJ, Yang SK, Jung HL. Comparison of immunomodulatory properties of mesenchymal stem cells derived

[9] Kidd S, Spaeth E, Watson K, Burks J, Lu H, Klopp A, Andreeff M, Marini FC. Origins of the tumor microenvironment: Quantitative assessment of adipose-derived and bone

[10] Jansen BJ, Gilissen C, Roelofs H, Schaap-Oziemlak A, Veltman JA, Raymakers RA, Jansen JH, Kögler G, Figdor CG, Torensma R. Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells and Development.

[11] Mosna F, Sensebé L, Krampera M. Human bone marrow and adipose tissue mesenchymal stem cells: A user's guide. Stem Cells and Development. 2010;**19**:1449-1470

[12] Liu ZJ, Zhuge Y, Velazquez OC. Trafficking and differentiation of mesenchymal stem

[13] Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nature

[14] Sharma RR, Pollock K, Hubel A, McKenna D.Mesenchymal stem or stromal cells: A review of clinical applications and manufacturing practices. Transfusion. 2014;**54**:1418-1437 [15] Augello A, Tasso R, Negrini SM, Amateis A, Indiveri F, Cancedda R, Pennesi G. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. European Journal of Immunology. 2005;**35**:1482-1490

[16] Haddad R, Saldanha-Araujo F. Mechanisms of T-cell immunosuppression by mesenchymal stromal cells: What do we know so far? BioMed Research International. 2014;**2014**:1-14.

[17] Najar M, Raicevic G, Kazan HF, De Bruyn C, Bron D, Toungouz M, Lagneaux L. Immunerelated antigens, surface molecules and regulatory factors in human-derived mesenchymal stromal cells: The expression and impact of inflammatory priming. Stem Cell

[18] Skalnikova HK. Proteomic techniques for characterisation of mesenchymal stem cell

son of their tropism towards gliomas. PLoS One. 2013;**8**:e58198

from adult human tissues. Cellular Immunology. 2009;**259**:150-156

National Academy of Sciences. 2010;**107**:21653-21658

marrow–derived stroma. PLoS One. 2012;**7**:e30563

cells. Journal of Cellular Biochemistry. 2009;**106**:984-991

Article ID: 216806, https://doi.org/10.1155/2014/216806

Reviews and Reports. 2012;**8**:1188-1198

secretome. Biochimie. 2013;**95**:2196-2211

Reviews Immunology. 2008;**8**:726

2010;**19**:481-490

2 Centro de Medicina Regenerativa, Universidad del Desarrollo, Santiago, Chile
