**2.7. Use of placental mesenchymal stem/stromal cells in urological diseases**

Stress urinary incontinence (SUI) is a widespread disorder, commonly associated with childbirth, with a detrimental impact on the quality of life. SUI triggers a weakening of muscles and ligaments causing involuntary leakage of urine during physical activity, sneezing, or coughing. Surgical intervention to place a tissue sling that provides support to the urethra is the usual therapeutic action.

Animal models of SUI have been employed to prove the benefits of cell therapy in this pathology. Periurethral injection of myogenic differentiated PMSC in SUI mice restored the urethral sphincter to apparently normal histology and function [89].
