**Abstract**

[97] Petit PC, Fine DH, Vásquez GB, Gamero L, Slaughter MS, Dasse KA.The pathophysiology of nitrogen dioxide during inhaled nitric oxide therapy. ASAIO Journal. 2017;**63**(1):7-13 [98] Depayras S, Kondakova T, Merlet-Machour N, Heipieper HJ, Barreau M, Catovic C,

virulence. International Journal of Environmental Impacts. 2018;**1**(2):183-192. https://

www.witpress.com/elibrary/ei-volumes/1/2/1806#.WliS\_8echfo.mendeley

44 Emerging Pollutants - Some Strategies for the Quality Preservation of Our Environment

on *P. fluorescens* strain in the membrane adaptation and

et al. Impact of gaseous NO2

Determination of emerging pollutants such as UV-filters in environmental samples is very important because they have been proven to have harmful effects on human and aquatic life. In this study, a simple, fast and inexpensive method combining solid phase extraction (SPE) and UV spectrophotometry was developed for simultaneous preconcentration and determination of benzophenone and sulisobenzone in wastewater samples. The effect of factors affecting the preconcentration of UV-filters was optimized using univariate and multivariate approach. Under optimized conditions, the limits of detection (LOD), limits of quantification (LOQ) and preconcetration factors were in the range of 0.15–0.28 and 0.50–0.93 μg L−1, 50–55, respectively. The dynamic linear range was up to 250 μg L−1 for benzophenone and sulisobenzone. In addition, the intra- and inter-day precisions were 3.1–3.3 and 4.5–5.2%, respectively. The developed method was successfully applied to determine UV filters in wastewater samples attaining satisfactory recoveries over the range of 99.3–100.7%. The concentration of the target pollutants in wastewater samples ranged from 6.83 to 85.67 μg L−1.

**Keywords:** solid phase extraction, emerging organic pollutants, UV-filters, response surface methodology, UV-Vis spectrophotometry, endocrine disruptors
