**Meet the editor**

Dr. Mohamed Ahmed El-Esawi is currently a visiting research fellow at the University of Cambridge in the United Kingdom and an associate professor of Molecular Genetics at Botany Department of Tanta University in Egypt. Dr. El-Esawi received his BSc and MSc degrees from Tanta University and his PhD degree in Plant Genetics and Molecular Biology from Dublin Institute

of Technology in Ireland. Afterwards, Dr. El-Esawi joined the University of Warwick in the UK, University of Sorbonne (Paris VI) in France and University of Leuven (KU Leuven) in Belgium as a visiting research fellow. His research focuses on plant genetics, genomics, molecular biology, molecular physiology, developmental biology, plant-microbe interaction and bioinformatics. He has authored several international journal articles and book chapters and participated in more than 60 conferences and workshops worldwide. Dr. El-Esawi is currently involved in several research projects in biological sciences.

Contents

**Preface VII**

**Mechanisms 1** Mohamed A. El-Esawi

Hülya Çakmur

Chapter 2 **Circadian Rhythm and Chronobiology 5**

**Chronotoxicology 15**

**Series Perspective 33**

Angelova

Olivier Le Bon

**Diseases 79**

Pavol Svorc

**in Rat Model 107**

Chapter 5 **Jet Lag 59**

Chapter 3 **Circadian Clock Gene Expression and Drug/Toxicant**

Chapter 1 **Introductory Chapter: Circadian Rhythms and Their Molecular**

**Interactions as Novel Targets of Chronopharmacology and**

Ruben Fossion, Ana Leonor Rivera, Juan C. Toledo-Roy and Maia

Jie Liu, Huan Li, Shangfu Xu, Yunyan Xu and Chang Liu

Chapter 4 **Quantification of Irregular Rhythms in Chronobiology: A Time-**

Chapter 6 **Features of Circadian Rhythms in Patients with Cerebrovascular**

Chapter 7 **Chronobiology of Acid-Base Balance under General Anesthesia**

Elena Kostenko and Liudmila Petrova

Chapter 8 **Sudden Death Circadian Rhythm in Chagasic Patients Compared to Non-Chagasic Patients 145** Juan Marques, Iván Mendoza and Claudia Suarez
