**Section 4 Apoptosis at Resistance to Chemotherapy and at Electromagnetic Radiation 123**


Preface

must read source for the scientist in the field.

Apoptosis is an essential biochemical process in cell turnover, development, and chemicalinduced cell death. Current knowledge and ongoing research of apoptosis highlight our un‐ derstanding in designing therapeutic approaches for several diseases. This book covers four main sections: Apoptosis and necrosis, Apoptosis inducers, Proteasome and signaling path‐ ways in apoptosis, and Radiation based apoptosis. The first section implicitly describes dif‐ ferences between apoptosis and necrosis processes. These two concepts were discussed on acute kidney injury. The following section elaborates small molecule induced apoptosis. Ar‐ senic inducing apoptosis in cancer cells and more specifically artonin inducing effect in breast cancer were discussed. Further, calcium activated potassium channel link to cell sur‐ vival and death was reported in this section. Then, in the third section two excellent research reports highlighted the importance of proteasome and signaling pathway: Proteasome acti‐ vator PA28gamma impact on apoptosis and signalling pathways targeted by protozan para‐ sites to modulate apoptosis and finally Apoptosis at Resistance to Chemotherapy and at Electromagnetic Radiation have been covered in the last section. Overall, the book content provides a unique perspective to the scientists and examines pathways for manipulating apoptosis. Several diseases suppress apoptosis and help cell survival therefore; the selective control of apoptosis may provide therapeutical benefits. Designing small molecules to trig‐ ger apoptosis may further augment the therapeutic effect. For these reasons, the book is a

**Prof. Dr. Yusuf tutar**

Faculty of Pharmacy Üsküdar, Istanbul, Turkey

**Dr. Lütfi Tutar**

Kırşehir, Turkey

University of Health Sciences

Kırşehir Ahi Evran University
