6. Conclusion and remarks

Currently, several biomarkers for diagnosis are available in research laboratories, with expensive and sophisticated equipment requiring trained operators, precluding their direct application for field use.

Due to the specific characteristics associated to serological methodologies, they are accepted as the ideal diagnosis approach for both human and animal use, enabling epidemiological studies. Still, a significant limitation of serological tests is their capacity to detect asymptomatic cases. Further challenges associated to the advent of vaccination still need to be addressed.

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Ultimately, the goal is to find biomarkers that detect different clinical forms of the disease that can be used universally in a rapid diagnosis kit.
